Canine IL1B Antibody

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Catalog #: ABCESPA1393
Product Features
Immunogen: Recombinant Canine IL-1 beta protein 
Clonality:  Rabbit PAb
Cloneno:
Isotype: Rabbit IgG
Buffer: 0.2 μm filtered solution in PBS
Reactivity: Canine
Specificity: Canine IL-1 beta
Application: ELISA
Recommend dilution:  ELISA: 0.5-1.0 μg/mL. This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Canine IL-1 beta. The detection limit for Canine IL-1 beta is <0.039 ng/well.
Storage: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Background: Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).
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