| Product Features | |
|---|---|
| Immunogen: | Recombinant Cynomolgus IL6 / Interleukin-6 protein |
| Clonality: | Rabbit PAb |
| Cloneno: | |
| Isotype: | Rabbit IgG |
| Buffer: | 0.2 μm filtered solution in PBS with 5% trehalose |
| Reactivity: | Cynomolgus |
| Specificity: | Cynomolgus IL6 / Interleukin-6 |
| Application: | ELISA, IHC-P |
| Recommend dilution: | ELISA: 0.1-0.2 μg/mL. This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Cynomolgus IL6 / Interleukin-6. The detection limit for Cynomolgus IL6 / Interleukin-6 is approximately < 0.039 ng/well. IHC-P: 0.1-1 μg/mL |
| Storage: | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
| Background: | Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity. |
Cynomolgus IL6 Antibody
$322.00 – $847.00