Product Features | |
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Immunogen: | Recombinant Rhesus IL6 / IL-6 protein |
Clonality: | Rabbit PAb |
Cloneno: | |
Isotype: | Rabbit IgG |
Buffer: | 0.2 μm filtered solution in PBS |
Reactivity: | Cynomolgus |
Specificity: | Rhesus IL6 / IL-6 |
Application: | ELISA |
Recommend dilution: | ELISA: 0.5-1.0 μg/mL. This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Rhesus IL6 / IL-6. The detection limit for Rhesus IL6 / IL-6 is <0.039 ng/well. |
Storage: | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. |
Background: | Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity. |
Rhesus IL6 Antibody
$322.00 – $847.00