Rhesus IL6 Antibody

$322.00$847.00

Catalog #: ABCESPA1468
Product Features
Immunogen: Recombinant Rhesus IL6 / IL-6 protein 
Clonality:  Rabbit PAb
Cloneno:
Isotype: Rabbit IgG
Buffer: 0.2 μm filtered solution in PBS
Reactivity: Cynomolgus
Specificity: Rhesus IL6 / IL-6
Application: ELISA
Recommend dilution:  ELISA: 0.5-1.0 μg/mL. This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Rhesus IL6 / IL-6. The detection limit for Rhesus IL6 / IL-6 is <0.039 ng/well.
Storage: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Background: Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
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