| Product Features | |
|---|---|
| Immunogen: | Recombinant Cynomolgus Thrombopoietin / THPO protein |
| Clonality: | Rabbit PAb |
| Cloneno: | |
| Isotype: | Rabbit IgG |
| Buffer: | Produced in rabbits immunized with purified, recombinant Cynomolgus Thrombopoietin / THPO (rCynomolgus Thrombopoietin / THPO; Catalog#90004-C08H; Met 1-Gly 353). Total IgG was purified by Protein A affinity chromatography. |
| Reactivity: | Cynomolgus |
| Specificity: | Cynomolgus Thrombopoietin / THPO |
| Application: | ELISA |
| Recommend dilution: | ELISA: 0.5-1.0 μg/mL. This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Cynomolgus THPO. The detection limit for Cynomolgus THPO is approximately 0.0195 ng/well. |
| Storage: | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
| Background: | Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. Thrombopoietin protein stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. Thrombopoietin protein is involved in cardiovascular disease as it regulates megakaryocyte development and enhances platelet adhesion/aggregation. It has been identified that surface c-MPL, the receptor for thrombopoietin protein, binds to the ligand and mediates the action. |
Cynomolgus Thrombopoietin/THPO Antibody
$322.00 – $847.00