| Product Features | |
|---|---|
| Immunogen: | Recombinant Cynomolgus KIM-1 / TIM1 / HACVR1 Protein |
| Clonality: | Rabbit MAb |
| Cloneno: | 2 |
| Isotype: | Rabbit IgG |
| Buffer: | This antibody was obtained from a rabbit immunized with purified, recombinant Cynomolgus KIM-1 / TIM1 / HACVR1 (rC KIM-1 / TIM1 / HACVR1; Catalog#90006-C08H; Met 1-Val 135). |
| Reactivity: | Cynomolgus |
| Specificity: | Cynomolgus KIM-1 / TIM1 / HACVR1 No cross-reactivity in ELISA with Mouse KIM1 Human TIMD3 |
| Application: | ELISA |
| Recommend dilution: | ELISA: 0.1-0.2 μg/mL. This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Cynomolgus HAVCR1. The detection limit for Cynomolgus HAVCR1 is approximately 0.0049 ng/well. |
| Storage: | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
| Background: | Human HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â… integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling. |
Cynomolgus KIM1/TIM1 Antibody
$322.00 – $847.00