| Product Features | |
|---|---|
| Immunogen: | Recombinant Rhesus CD16 / FCGR3 protein |
| Clonality: | Mouse MAb |
| Cloneno: | 1 |
| Isotype: | Mouse IgG1 |
| Buffer: | 0.2 μm filtered solution in PBS with 5% trehalose |
| Reactivity: | Cynomolgus |
| Specificity: | Rhesus CD16 / FCGR3Has cross-reactivity in ELISA withHuman CD16aHuman CD16bNo cross-reactivity in ELISA withHuman CD32AHuman CD32bHuman CD64Human cell lysate (293 cell line) |
| Application: | ELISA |
| Recommend dilution: | ELISA: 0.5-1 μg/mL. This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Rhesus FCGR3. The detection limit for Rhesus FCGR3 is approximately 0.00975 ng/well. |
| Storage: | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
| Background: | Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes. |
Rhesus CD16 Antibody
$322.00 – $847.00